Embo Signal Mission Statement
To spread the insight to the medical community that
the smart use of cerebral embolus detection software will prevent strokes in all patients with an increased stroke risk.
We will achieve this mission by:
1. Releasing free EDS demo's that teach you how solid en gaseous emboli look like under different clinical conditions.
2. Providing the medical community the best software to detect solid and gaseous emboli in TCD recordings.
3. Providing teaching files with different types of
solid & gaseous emboli and artifacts in the bloodstream.
4. Providing lectures on stroke prevention by TCD embolus detection.
5. Free review and feedback your own TCD audio-files.
Inspirators of the EDS Pro development
Merrill Spencer Rune Aaslid Rob Ackerstaff Run
Additional TCD Stroke Prevention Initiatives
developed by R.W.M. Keunen MD PhD
The Haga Braincare Strategy
The Haga Braincare Stragey has been developed to reduce the burden of focal and global ischemia related to cardiac surgery. It is a dual strategy in which patients with cerebral flow states are identified prior to surgery by TCD Ultrasound and in which patients are monitored per--operatively by non-invasive NIRS cerebral oximetry. In a retrospective follow-up study we noticed a the Haga Teaching Hospital an extinction of postoperative hemodynamic strokes and a > 50 % reduction of the post operative delirium...
Current EDS Pro research
Embo Signal Achievements
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2007 Programmer Remco Hoogenboezem & vascular neurologist Ruud Keunen designed the first zero-crossing based embolus detection algorithm for discrimination for single solid emboli and artefacts from TCD audio recordings.
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2008 EDS has been CE certified, published and brought to the European Market.
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2009 Antonius Nieuwegein and University Medical Centre Utrecht amongst the first centres in Holland which started to monitor carotid surgery with EDS.
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2015 Over 10 Dutch Vascular Medical Centres uses over 15 EDS systems mainly to monitor carotid surgery
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2020 EDS is exclusively distributed on Delica TCD systems with a focus to serve European Medical Centres
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2021 EDS was presented in over 20 lectures and zoom meetings over Europe
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2022 Invited EDS lecture at University of Cambridge for Peter Smielewski and Marik Czosnyka
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2022 Semmelweis University Budapest is the 10th European Medical Centre that uses the EDS software to monitor Pulmonary Vene Isolation
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2022 EDS Medical and the Deventer hospital start a cooperation to validated the EDS PFO algorithm to detect gaseous emboli in TCD recordings.
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2023 EDS published a new Solid/Gaseous/Artefact Algorithm also presented at the 22th ESNCH Meeting Lisbon
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2023 EDS lectures at the Karolinska University Stockholm and University of Orebro Sweden
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2024 EDS published and validated a new PFO algorithm
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2025 EDS delivered to the Ansan University, Ansan, Korea
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2026 EDS first delivery in the USA at the Neurological Centre Dartmouth, New Hampshire
EDS Pro
EDS Pro is a validated and peer reviewed software for detecting both solid and gaseous emboli in the bloodstream. The EDS has been developed and validated by Dr. RWM Keunen, a Dutch vascular neurologist working at the Haga Teaching Hosipitals, The Hague, The Netherlands.
EDS Pro combines three clinically validated embolus detection algorithms with powerful rapid verification tools for long-term TCD recordings.
It helps TCD end-users to review Transient high-intensity signals efficiently and classify them according to the probability that they represent emboli or artefacts. EDS Pro includes three dedicated detection algorithms which can be used depending on the clinical situation.
The TIA and Stroke algorithms detects single solid emboli as seen in carotid artery stenosis and endocarditis.
The PFO algorithms detects gaseous emboli seen during PFO tests and PVI procedures.
The SGA algorithm discriminates presumed solid and presumed gaseous emboli and artefacts. This algorithm is applied during TAVI and cardio surgical procedures.
